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Item TypeName
Academic Article Molecular cloning and expression of rat kallistatin gene.
Academic Article Gene therapy in hypertension: adenovirus-mediated kallikrein gene delivery in hypertensive rats.
Academic Article Experimental kallikrein gene therapy in hypertension, cardiovascular and renal diseases.
Academic Article Transcription factor nuclear factor kappaB regulates the inducible expression of the human B1 receptor gene in inflammation.
Academic Article Kallikrein gene delivery attenuates hypertension and cardiac hypertrophy and enhances renal function in Goldblatt hypertensive rats.
Academic Article Atrial natriuretic peptide gene delivery reduces stroke-induced mortality rate in Dahl salt-sensitive rats.
Academic Article Human kallikrein gene delivery attenuates hypertension, cardiac hypertrophy, and renal injury in Dahl salt-sensitive rats.
Academic Article Atrial natriuretic peptide gene delivery attenuates hypertension, cardiac hypertrophy, and renal injury in salt-sensitive rats.
Academic Article Kallikrein gene delivery inhibits vascular smooth muscle cell growth and neointima formation in the rat artery after balloon angioplasty.
Academic Article Bradykinin B(1) receptor mediates inhibition of neointima formation in rat artery after balloon angioplasty.
Academic Article Adrenomedullin gene delivery attenuates hypertension, cardiac remodeling, and renal injury in deoxycorticosterone acetate-salt hypertensive rats.
Academic Article Novel roles of kallistatin, a specific tissue kallikrein inhibitor, in vascular remodeling.
Academic Article Adenovirus-mediated gene transfer for cardiovascular and renal diseases.
Academic Article Adenovirus-mediated kallikrein gene delivery reduces aortic thickening and stroke-induced death rate in Dahl salt-sensitive rats.
Academic Article Molecular cloning and analysis of the rat kallikrein-binding protein gene.
Academic Article Tissue kallikrein attenuates salt-induced renal fibrosis by inhibition of oxidative stress.
Academic Article Kallikrein gene delivery attenuates myocardial infarction and apoptosis after myocardial ischemia and reperfusion.
Academic Article Postischemic infusion of adrenomedullin protects against ischemic stroke by inhibiting apoptosis and promoting angiogenesis.
Academic Article The tissue kallikrein-kinin system protects against cardiovascular and renal diseases and ischemic stroke independently of blood pressure reduction.
Academic Article Tissue kallikrein protects against pressure overload-induced cardiac hypertrophy through kinin B2 receptor and glycogen synthase kinase-3beta activation.
Academic Article Roles of the P1, P2, and P3 residues in determining inhibitory specificity of kallistatin toward human tissue kallikrein.
Academic Article Tissue kallikrein promotes neovascularization and improves cardiac function by the Akt-glycogen synthase kinase-3beta pathway.
Academic Article Molecular cloning and primary structure of rat alpha 1-antitrypsin.
Academic Article Tissue kallikrein in cardiovascular, cerebrovascular and renal diseases and skin wound healing.
Academic Article Tissue kallikrein promotes prostate cancer cell migration and invasion via a protease-activated receptor-1-dependent signaling pathway.
Academic Article Inhibition of experimental lung metastasis by systemic lentiviral delivery of kallistatin.
Academic Article Kallistatin in blood pressure regulation transgenic and somatic gene delivery studies.
Academic Article Molecular cloning and sequence analysis of the mouse kallikrein-binding protein gene.
Academic Article Human endothelial nitric oxide synthase gene delivery promotes angiogenesis in a rat model of hindlimb ischemia.
Academic Article Co-localization of a kallikrein-like serine protease (arginine esterase A) and atrial natriuretic peptide in rat atrium.
Academic Article Renal kallikrein mRNA localization by in situ hybridization.
Academic Article Kallistatin antagonizes Wnt/?-catenin signaling and cancer cell motility via binding to low-density lipoprotein receptor-related protein 6.
Academic Article Tissue distribution and kininogen gene expression after acute-phase inflammation.
Academic Article A major difference of kallikrein-binding protein in spontaneously hypertensive versus normotensive rats.
Academic Article Special antigens on sperm from autoimmune infertile men.
Academic Article Immunocytochemical localization of a kallikrein-like serine protease (esterase A) in rat salivary glands.
Academic Article Identification and characterization of a tissue kallikrein in rat skeletal muscles.
Academic Article Sperm and seminal plasma antigens from autoimmune men induce immunological infertility.
Academic Article Identification of latent tissue kallikrein, prolactin and growth hormone secretion in GH3 pituitary cells using modified radioimmunoassays.
Academic Article Comparison of the distribution of tissue kallikrein and esterase A, a kallikrein-like enzyme, in rat kidney using specific monoclonal antibodies.
Academic Article Gene therapy with human tissue kallikrein reduces hypertension and hyperinsulinemia in fructose-induced hypertensive rats.
Academic Article Kallistatin: a novel human tissue kallikrein inhibitor. Purification, characterization, and reactive center sequence.
Academic Article Comparative studies on P2 specificity of wild-type rat tissue kallikrein, Y99H:W215G mutant and tonin.
Academic Article Structure and chromosomal localization of the gene (BDKRB2) encoding human bradykinin B2 receptor.
Academic Article Molecular cloning, sequence analysis, and chromosomal localization of the human protease inhibitor 4 (kallistatin) gene (PI4).
Academic Article Kallistatin: a novel human serine proteinase inhibitor. Molecular cloning, tissue distribution, and expression in Escherichia coli.
Academic Article Screening of complementary DNA library using radiolabeled antigen.
Academic Article Regulatory elements in the promoter region of the renal kallikrein gene in normotensive vs hypertensive rats.
Academic Article Identification and characterization of two promoters of rat kallikrein-binding protein gene.
Academic Article Tissue kallikrein inhibitors in mammals.
Academic Article Evolution of the kallikrein gene family.
Academic Article High-salt diet upregulates kininogen and downregulates tissue kallikrein expression in Dahl-SS and SHR rats.
Academic Article Adenovirus-mediated delivery of human kallistatin gene reduces blood pressure of spontaneously hypertensive rats.
Academic Article Kallikrein-binding protein levels are reduced in the retinas of streptozotocin-induced diabetic rats.
Academic Article Biochemistry, regulation and potential function of kallistatin.
Academic Article Tissue-specific expression and promoter analyses of the human tissue kallikrein gene in transgenic mice.
Academic Article Expression of human tissue kallikrein in rat salivary glands and its secretion into circulation following adenovirus-mediated gene transfer.
Academic Article Kallikrein gene therapy: a new strategy for hypertensive diseases.
Academic Article Kallikrein/kinin protects against myocardial apoptosis after ischemia/reperfusion via Akt-glycogen synthase kinase-3 and Akt-Bad.14-3-3 signaling pathways.
Academic Article Kallikrein gene transfer reduces renal fibrosis, hypertrophy, and proliferation in DOCA-salt hypertensive rats.
Academic Article Kallikrein/kinin protects against gentamicin-induced nephrotoxicity by inhibition of inflammation and apoptosis.
Academic Article Tissue kallikrein reverses insulin resistance and attenuates nephropathy in diabetic rats by activation of phosphatidylinositol 3-kinase/protein kinase B and adenosine 5'-monophosphate-activated protein kinase signaling pathways.
Academic Article Upregulation of kallistatin expression in rheumatoid joints.
Academic Article Nitric oxide mediates cardiac protection of tissue kallikrein by reducing inflammation and ventricular remodeling after myocardial ischemia/reperfusion.
Academic Article Tissue kallikrein and kinin infusion promotes neovascularization in limb ischemia.
Academic Article Kruppel-like factor 4 is a novel mediator of Kallistatin in inhibiting endothelial inflammation via increased endothelial nitric-oxide synthase expression.
Academic Article A novel signaling pathway of tissue kallikrein in promoting keratinocyte migration: activation of proteinase-activated receptor 1 and epidermal growth factor receptor.
Academic Article Sex dimorphism and estrogen regulation of kininogens in rat serum, adrenal gland and kidney.
Academic Article Depletion of endogenous kallistatin exacerbates renal and cardiovascular oxidative stress, inflammation, and organ remodeling.
Academic Article Circulating autoantibodies to mammalian tissue kallikreins.
Academic Article Biochemical characterization and substrate specificity of rat prostate kallikrein (S3): comparison with tissue kallikrein, tonin and T-kininogenase.
Academic Article Molecular cloning, purification and in situ localization of human colon kallikrein.
Academic Article Localization of kallikrein gene family proteases in rat tissues.
Academic Article Molecular cloning and characterization of a novel kallikrein transcript in colon and its distribution in human tissues.
Academic Article Expression and characterization of rat kallikrein-binding protein in Escherichia coli.
Academic Article Molecular cloning and characterization of rKlk10, a cDNA encoding T-kininogenase from rat submandibular gland and kidney.
Academic Article High level expression of human tissue kallikrein in the circulation induces hypotension in transgenic mice.
Academic Article Genomic DNA sequence, expression, and chromosomal localization of the human B1 bradykinin receptor gene BDKRB1.
Academic Article Structure and chromosomal localization of the human prostasin (PRSS8) gene.
Academic Article Cellular localization of bradykinin B1 receptor mRNA in the human kidney.
Academic Article Expression of kallikrein-binding protein and alpha 1-antitrypsin genes in response to sex hormones, growth, inflammation and hypertension.
Academic Article Tissue kallikrein-binding protein reduces blood pressure in transgenic mice.
Academic Article DNA polymorphisms in the 5'-flanking region of the human tissue kallikrein gene.
Academic Article Prolonged reduction of high blood pressure with human nitric oxide synthase gene delivery.
Concept Kruppel-Like Transcription Factors
Concept Nephritis, Interstitial
Concept Blotting, Southern
Concept Enzyme-Linked Immunosorbent Assay
Concept Extracellular Matrix
Concept Age Factors
Concept Neutrophils
Concept Disease Models, Animal
Concept Fibroblasts
Concept Injections, Intramuscular
Concept Sperm Motility
Concept Kidney Glomerulus
Concept Sequence Analysis, DNA
Concept Ventricular Function
Concept Glycogen
Concept Rats, Inbred WKY
Concept Transforming Growth Factor beta
Concept Microscopy, Electron
Concept Blood Urea Nitrogen
Concept Lung Neoplasms
Concept Salivary Glands
Concept Kallikrein-Kinin System
Concept Cyclin D1
Concept Catalase
Concept Data Interpretation, Statistical
Concept Blood Pressure
Concept Protein Processing, Post-Translational
Concept Kaplan-Meier Estimate
Concept Interferon-gamma
Concept Cerebral Infarction
Concept Kininogens
Concept Fructose
Concept Chromosomes, Human, Pair 16
Concept Restriction Mapping
Concept Multigene Family
Concept Flow Cytometry
Concept Introns
Concept Proportional Hazards Models
Concept Mitogen-Activated Protein Kinases
Concept Genetic Therapy
Concept Prolactin
Concept Injections, Intraventricular
Concept Rats, Inbred Strains
Concept Neurologic Examination
Concept Cell Division
Concept Laser-Doppler Flowmetry
Concept p38 Mitogen-Activated Protein Kinases
Concept Fetal Blood
Concept Intercellular Adhesion Molecule-1
Concept Receptors, Endothelin
Concept Metabolic Clearance Rate
Concept Drinking
Concept Mutagenesis, Site-Directed
Concept Nitric Oxide
Concept DNA, Complementary
Concept Fluorescent Antibody Technique
Concept Body Weight
Concept Autophagy
Concept Creatine
Concept Kidney Diseases
Concept Adenoviruses, Human
Concept Sensitivity and Specificity
Concept Vascular Cell Adhesion Molecule-1
Concept Endothelium, Vascular
Concept Telomerase
Concept Aorta, Thoracic
Concept Cell Survival
Concept Injections
Concept Sodium-Potassium-Exchanging ATPase
Concept Treatment Outcome
Concept Mitogen-Activated Protein Kinase Kinases
Concept Macrophages
Concept Kidney Failure, Chronic
Concept Vascular Resistance
Concept Choroid
Concept Genes, Dominant
Concept Rats, Inbred Lew
Concept TATA Box
Concept Serpins
Concept Cricetinae
Concept Hemagglutinins, Viral
Concept Collagen Type I
Concept Hyperinsulinism
Concept Dogs
Concept Amino Acid Substitution
Concept Progesterone
Concept Diabetic Retinopathy
Concept Binding, Competitive
Concept Blotting, Northern
Concept Regional Blood Flow
Concept Heparin
Concept Mitogen-Activated Protein Kinase 1
Concept Genes
Concept Proto-Oncogene Proteins c-bcl-2
Concept Coronary Circulation
Concept Intensive Care Units
Concept Random Allocation
Concept Mice, Knockout
Concept Submandibular Gland
Concept Saccharomyces cerevisiae
Concept Pituitary Neoplasms
Concept Renal Insufficiency
Concept Antibodies
Concept Influenza, Human
Concept Constriction, Pathologic
Concept Lac Operon
Concept Coronary Artery Disease
Concept Hypertension, Pulmonary
Concept Stroke
Concept Mortality
Concept Antiviral Agents
Concept Carotid Stenosis
Concept Hydrogen Peroxide
Concept Blotting, Western
Concept Mesangial Cells
Concept Pancreatic Neoplasms
Concept Iodine Radioisotopes
Concept C-Reactive Protein
Concept Kidney Cortex
Concept Bradykinin
Concept Lipopolysaccharides
Concept Exocrine Glands
Concept Ventricular Remodeling
Concept Injections, Subcutaneous
Concept Enhancer Elements, Genetic
Concept Acute Lung Injury
Concept Diabetes Mellitus
Concept Anti-Inflammatory Agents, Non-Steroidal
Concept Renin-Angiotensin System
Concept Hypertension, Renal
Concept Rats, Inbred BN
Concept Diabetic Nephropathies
Concept Acetylcysteine
Concept AMP-Activated Protein Kinases
Concept Infusions, Intravenous
Concept Lymphokines
Concept Up-Regulation
Concept Kinins
Concept Durapatite
Concept Caspase 3
Concept Serine Proteinase Inhibitors
Concept Thy-1 Antigens
Concept Spermatozoa
Concept Radioimmunoassay
Concept Enzyme Induction
Concept Cerebrovascular Disorders
Concept Trypsin Inhibitors
Concept Mice
Concept Rats, Inbred WF
Concept Aging
Concept Infusions, Intra-Arterial
Concept Desoxycorticosterone
Concept Genetic Variation
Concept Insulin Resistance
Concept Umbilical Veins
Concept Immunoenzyme Techniques
Concept Rats, Inbred SHR
Concept Kinetics
Concept Isoenzymes
Concept Mitogen-Activated Protein Kinase 3
Concept Microscopy, Confocal
Concept Cardiac Catheterization
Concept Renin
Concept Tumor Necrosis Factor-alpha
Concept Isoelectric Focusing
Concept Gene Expression Regulation, Developmental
Concept Chromatography, High Pressure Liquid
Concept Drug Antagonism
Concept Proteoglycans
Concept Hydroxyapatites
Concept Eye
Concept Estrogens
Concept Exons
Concept Asialoglycoproteins
Concept Renal Circulation
Concept Diabetes Mellitus, Type 2
Concept Hypertrophy
Concept bcl-Associated Death Protein
Concept Ovariectomy
Concept Codon
Concept Mice, Inbred C57BL
Concept CD3 Complex
Concept Repetitive Sequences, Nucleic Acid
Concept Gene Expression Regulation
Concept Enzyme Activation
Concept Sequence Deletion
Concept Cyclin-Dependent Kinase Inhibitor p16
Concept Nitrogen Oxides
Concept Mice, Transgenic
Concept T-Lymphocytes
Concept Glomerulosclerosis, Focal Segmental
Concept Oxygen
Concept Kidney Function Tests
Concept Transforming Growth Factor beta1
Concept Injections, Intraperitoneal
Concept Heart Rate
Concept Glomerular Filtration Rate
Concept Proteinuria
Concept DNA Mutational Analysis
Concept Xenograft Model Antitumor Assays
Concept Carotid Artery Injuries
Concept Severity of Illness Index
Concept Lymphoid Tissue
Concept Cell Proliferation
Concept Survival Rate
Concept Genomic Library
Concept Humans
Concept 14-3-3 Proteins
Concept Gonadal Steroid Hormones
Concept Down-Regulation
Concept Brain Ischemia
Concept Cattle
Concept Transgenes
Concept Prostate
Concept Organ Size
Concept Laminin
Concept Chromatography, Ion Exchange
Concept Rats, Inbred Dahl
Concept Urinary Bladder Diseases
Concept alpha 1-Antitrypsin
Concept Suppressor of Cytokine Signaling Proteins
Concept DNA, Viral
Concept Escherichia coli
Concept Reactive Oxygen Species
Concept Rabbits
Concept Kallikreins
Concept Cardiomegaly
Concept Genetic Engineering
Concept Interleukin-1
Concept Electrophoresis, Polyacrylamide Gel
Concept Angioplasty, Balloon
Concept Pneumonia
Concept Estradiol
Concept DNA, Recombinant
Concept Leg
Concept Gene Expression Regulation, Viral
Concept Genes, Reporter
Concept Nucleic Acid Hybridization
Concept Infertility, Male
Concept Autoantibodies
Concept Caspases
Concept Uterine Contraction
Concept Glycogen Synthase Kinase 3
Concept Gene Expression Regulation, Enzymologic
Concept Chromosomes, Human, Pair 14
Concept Blood Glucose
Concept Endotoxemia
Concept Antibodies, Monoclonal
Concept Chymotrypsin
Concept Pituitary Gland, Anterior
Concept Retina
Concept Survival Analysis
Concept Systole
Concept Arthritis, Rheumatoid
Concept Sex Factors
Concept Analysis of Variance
Concept Reverse Transcriptase Polymerase Chain Reaction
Concept Protease Inhibitors
Concept Thymus Gland
Concept Recombinant Fusion Proteins
Concept Interleukin-1beta
Concept Cyclosporine
Concept Pancreatic Elastase
Concept Deoxyribonuclease HindIII
Concept Sequence Alignment
Concept Polymorphism, Restriction Fragment Length
Concept Haplorhini
Concept Blood Chemical Analysis
Concept Genome, Human
Concept Dipeptides
Concept Transduction, Genetic
Concept Receptor, PAR-1
Concept Carcinoma, Renal Cell
Concept Polymorphism, Genetic
Concept Lymph Nodes
Concept Endothelial Growth Factors
Concept Mice, Nude
Concept Gene Library
Concept Case-Control Studies
Concept Hemodynamics
Concept Chemokine CCL2
Concept Kallidin
Concept Albuminuria
Concept Gene Expression Regulation, Neoplastic
Concept Extracellular Signal-Regulated MAP Kinases
Concept Predictive Value of Tests
Concept Reproducibility of Results
Concept Fas Ligand Protein
Concept Guinea Pigs
Concept JNK Mitogen-Activated Protein Kinases
Concept Prospective Studies
Concept Streptococcus pyogenes
Concept Kidney Neoplasms
Concept Rats
Concept Chromosome Mapping
Concept Growth
Concept Collagen
Concept Autoradiography
Concept Interleukin-6
Concept Vitreous Body
Concept Hemoglobins
Concept Genistein
Concept Spleen
Concept Rats, Mutant Strains
Concept In Situ Hybridization
Concept Vasodilation
Concept Immunoelectrophoresis
Concept Creatinine
Concept Tissue Kallikreins
Concept Parotid Gland
Concept Enzyme Inhibitors
Concept Hypertension, Renovascular
Concept Rats, Wistar
Concept Testosterone
Concept DNA Restriction Enzymes
Concept Serine Endopeptidases
Concept Femoral Artery
Concept Gentamicins
Concept Transfection
Concept Point Mutation
Concept Cyclin-Dependent Kinase Inhibitor p27
Concept Rats, Sprague-Dawley
Concept Peptidyl-Dipeptidase A
Concept Ciliary Body
Concept Polymerase Chain Reaction
Concept Carboxylic Ester Hydrolases
Concept Culture Media, Conditioned
Concept Apoptosis Regulatory Proteins
Concept Myocardial Contraction
Concept Colon
Concept Ultrasonography
Concept Gene Deletion
Concept Mice, Inbred DBA
Concept Risk Assessment
Concept In Situ Hybridization, Fluorescence
Concept Superoxides
Concept Neovascularization, Physiologic
Concept Genetic Vectors
Concept MicroRNAs
Concept Hydrogen-Ion Concentration
Concept NADPH Oxidases
Concept MAP Kinase Kinase 4
Concept Promoter Regions, Genetic
Concept Diabetes Mellitus, Experimental
Concept Brain Infarction
Concept Phosphatidylinositol 3-Kinases
Concept Cyclic AMP
Concept HMGB1 Protein
Concept Base Sequence
Concept Alleles
Concept Plasmids
Concept Follow-Up Studies
Concept Cloning, Molecular
Concept Aldosterone
Concept Immunosorbent Techniques
Concept Gene Knockdown Techniques
Concept Transcriptional Activation
Concept In Situ Nick-End Labeling
Concept Immunohistochemistry
Concept Drug Combinations
Concept Injections, Intravenous
Concept Gene Transfer Techniques
Concept Cytomegalovirus
Concept Heart Function Tests
Concept Immunoblotting
Concept Gene Dosage
Concept Matrix Metalloproteinases
Academic Article Tissue kallikrein-kinin therapy in hypertension and organ damage.
Academic Article Kallistatin ameliorates influenza virus pathogenesis by inhibition of kallikrein-related peptidase 1-mediated cleavage of viral hemagglutinin.
Academic Article Kallistatin inhibits TGF-?-induced endothelial-mesenchymal transition by differential regulation of microRNA-21 and eNOS expression.
Academic Article Kallistatin induces breast cancer cell apoptosis and autophagy by modulating Wnt signaling and microRNA synthesis.
Academic Article Kallistatin reduces vascular senescence and aging by regulating microRNA-34a-SIRT1 pathway.
Academic Article Kallistatin: double-edged role in angiogenesis, apoptosis and oxidative stress.
Academic Article Role of Kallistatin Treatment in Aging and Cancer by Modulating miR-34a and miR-21 Expression.
Academic Article Kallistatin attenuates endothelial senescence by modulating Let-7g-mediated miR-34a-SIRT1-eNOS pathway.
Academic Article Reduced Plasma Kallistatin Is Associated With the Severity of Coronary Artery Disease, and Kallistatin Treatment Attenuates Atherosclerotic Plaque Formation in Mice.
Academic Article Protective Role of Endogenous Kallistatin in Vascular Injury and Senescence by Inhibiting Oxidative Stress and Inflammation.
Concept Acute Kidney Injury
Concept Plaque, Atherosclerotic
Concept Epithelial-Mesenchymal Transition
Concept Wnt3A Protein
Concept Primary Cell Culture
Concept Optical Imaging
Concept Caspase Inhibitors
Concept Suppressor of Cytokine Signaling 3 Protein
Concept Glycogen Synthase Kinase 3 beta
Concept Bcl-2-Like Protein 11
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